Cast off for the vacation of a lifetime with a Mexico cruise deal from Priceline Cruises. These incredible sailings let you experience the stunning scenery, tropical activities and pristine beaches of Baja Mexico and the Mexican Riviera. Whether you want to unwind, enjoy fabulous dining, or find new thrills, a Mexico cruise offers something for everyone.

Mexico cruises from San Diego, San Francisco or Los Angeles let you explore all Mexico's Pacific Coast has to offer. Make port in Baja hotspots like Cabo San Lucas, San Jose Del Cabo and Todos Santos, where your options for beautiful beaches, exciting watersports and exciting nightlife are endless. Head further south on a Mexican Riviera cruise, where ports include Acapulco, known for its popular beaches and thrilling cliff diving, and Puerto Vallarta, a slice of calm, quite paradise surrounded by turquoise waters. Wherever your Mexico cruise takes you, you can expect plenty of beachside relaxation, all-season sunshine and once-in-a-lifetime adventures.

For a truly carefree getaway, look no further. On a cruise to Mexico, your resort tours with you - meaning you'll explore a variety of destinations without ever having to unpack or arrange accommodations in each new city. Whichever cruise line you choose, getting there will be half the fun. Nearly everything onboard is included in your cruise price, like fun kids' programs, entertaining nightlife, delectable dining and world-class accommodations. Plus, when you book your sailing with Priceline Cruises, you're guaranteed to get the best Mexico cruise deal.